ImmGen is a multi-center consortium but its work, and the databrowsers that it develops for community use, are supported by a grant administered at Harvard Medical School. It was thus among those affected by the mass termination of NIH grants to Harvard. We hope to reverse this decision, or align alternative funding, but the resource that ImmGen provides to more than 10,000 immunologists worldwide is threatened.
We would be most grateful for short emails of support, sent to ImmgenATgmail.com or to your US Senator (if applicable), or to whoever you think could valuably support the ImmGen mission.
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Early ImmGenMaps, an open-source cartography of the immune system.
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Early transcriptional effects of inflammatory cytokines reveal highly redundant cytokine networks.
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Microheterogeneity in the Kinetics and Sex-Specific Response to Type I IFN.
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The interweaved signatures of common-gamma-chain cytokines across immunologic lineages.
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Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes.
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Pubmed |
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A microRNA expression and regulatory element activity atlas of the mouse immune system.
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Pubmed |
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The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments
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Pubmed |
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Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes.
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Pubmed |
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Deep learning of immune cell differentiation.
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Pubmed |
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ImmGen at 15 |
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Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-γ in NK cells. |
Pubmed |
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ImmGen report: sexual dimorphism in the immune system transcriptome. |
Pubmed |
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The cis-Regulatory Atlas of the Mouse Immune System. |
Pubmed |
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Expression profiling of constitutive mast cells reveals a unique identity within the immune system. |
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Parsing the Interferon Transcriptional Network and Its Disease Associations. |
Pubmed |
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Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets. |
Pubmed |
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Gene expression during the generation and activation of mouse neutrophils: implication of novel functional and regulatory pathways. |
Pubmed |
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Variation and Genetic Control of Gene Expression in Primary Immunocytes across Inbred Mouse Strains. |
Pubmed |
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Immunological Genome Project and systems immunology. |
Pubmed |
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Beyond the transcriptome: completion of act one of the Immunological Genome Project. |
Pubmed |
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Transcriptome analysis identifies regulators of hematopoietic stem and progenitor cells. |
Pubmed |
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Differential splicing across immune system lineages. |
Pubmed |
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Identification of transcriptional regulators in the mouse immune system. |
Pubmed |
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The transcriptional landscape of αβ T cell differentiation. |
Pubmed |
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A network of high-mobility group box transcription factors programs innate interleukin-17 production. |
Pubmed |
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Transcriptional insights into the CD8+ T cell response to infection and memory T cell formation. |
Pubmed |
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Conservation and divergence in the transcriptional programs of the human and mouse immune systems. |
Pubmed |
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Decoding dendritic cell function through module and network analysis. |
Pubmed |
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Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells. |
Pubmed |
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Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. |
Pubmed |
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Molecular definition of the identity and activation of natural killer cells. |
Pubmed |
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Deciphering the transcriptional network of the dendritic cell lineage. |
Pubmed |
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Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks. |
Pubmed |
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Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes. |
Pubmed |
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Transcriptomes of the B and T lineages compared by multiplatform microarray profiling. |
Pubmed |
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The Immunological Genome Project: networks of gene expression in immune cells. |
Pubmed |