The immunological Genome Project is a collaborative group of Immunologists and Computational biologists who pool expertise and resources to perform a broad and deep dissection of the genome’s activity and its regulation in the immune system of the mouse.

The project defines gene expression patterns and programs, regulatory motifs and structures in the genome, their connectivity, and the factors that control them. The scope of the effort covers all immunological lineages ex vivo, from mast to memory T cells, as shaped by differentiation, genetic variation, activation and challenges. These data support the computational reconstruction of the genetic regulatory network that underlies immunocyte differentiation and activation. Beyond its potential for discovery, ImmGen is intended as a public resource. The data and metadata are accessible for direct browsing and exploration through tailored interfaces, aiming to serve knowledge, and not only facts.