Fine module 77 - -

Model's activators:

Symbol	Assignment	Title	min expression	max expression	mean weight	min weight	max weight
ELK4	C16 F66	ELK4, member of ETS oncogene family	6.72	10.80	0.12288	0.12288	0.12288
ETS1	C16 F66	E26 avian leukemia oncogene 1, 5' domain	5.71	11.93	0.10446	0.10446	0.10446
AES	C16 F67	amino-terminal enhancer of split	8.04	11.37	0.086711	0.0777	0.10074
NFATC3	C16 F66	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	6.63	11.83	0.063786	0.012007	0.068562
AFF3	C2 F17	AF4/FMR2 family, member 3	5.25	11.48	0.02439	0.02439	0.02439
HDAC7	C16 F77	histone deacetylase 7	6.73	11.36	0.012586	0.012586	0.012586
SP4	C1 F6	trans-acting transcription factor 4	5.38	9.55	0.010683	0.010683	0.010683
NFATC1	C17 F89	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	6.41	11.41	0.00068216	0.00068216	0.00068216

Model's repressors:

Symbol	Assignment	Title	min expression	max expression	mean weight	min weight	max weight	NCBI human gene summary
BATF3	C26 F147	basic leucine zipper transcription factor, ATF-like 3	5.82	9.31	-0.11896	-0.11896	-0.11896
CTBP2	C29 F162	C-terminal binding protein 2	5.85	9.31	-0.10563	-0.10563	-0.10563
HLX	C24 F120	H2.0-like homeobox	5.15	10.64	-0.079491	-0.079491	-0.079491
ETV3	C48 F249	ets variant gene 3	6.73	12.57	-0.010567	-0.047552	0
TBX21	C19 F99	T-box 21	5.13	12.06	-0.00043707	-0.0075647	0	Summary: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq].