Fine module 65 - Bad cluster


Model's activators:
SymbolAssignmentTitlemin expressionmax expressionmean weightmin weightmax weightNCBI human gene summary
SP4C1 F6trans-acting transcription factor 45.389.550.145850.145850.14585
ELK4C16 F66ELK4, member of ETS oncogene family6.7210.800.0758520.0758520.075852
ETS1C16 F66E26 avian leukemia oncogene 1, 5' domain5.7111.930.0645260.0645260.064526
AESC16 F67amino-terminal enhancer of split8.0411.370.0548450.0548450.054845
CBX3C8 F50chromobox homolog 3 (Drosophila HP1 gamma)5.5611.330.0389470.0389470.038947
TAF2C2 F17TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor5.979.820.0318450.0318450.031845
MYNNC3 F29myoneurin5.238.530.0264560.0264560.026456
MLLT3C18 F93myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 35.2810.570.0236280.0236280.023628
PKNOX1C1 F6Pbx/knotted 1 homeobox6.139.510.0173590.0173590.017359
NAB1C45 F222Ngfi-A binding protein 15.4010.110.01600.10548
RNF2C46 F237ring finger protein 25.979.510.0138190.00670080.015625
NFATC1C17 F89nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 16.4111.410.01191800.01283
NFATC3C16 F66nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 36.6311.830.00579520.000636940.19407
ZBTB25C1 F7zinc finger and BTB domain containing 254.259.260.00528600.054061
HCFC1C5 F42host cell factor C15.9111.300.002097600.047196Summary: This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq].
NFYBC5 F40nuclear transcription factor-Y beta6.079.600.0006810500.0011351
NPAS2C36 F196neuronal PAS domain protein 24.3410.080.0006291500.020223Summary: The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. A similar mouse protein may play a regulatory role in the acquisition of specific types of memory. It also may function as a part of a molecular clock operative in the mammalian forebrain. [provided by RefSeq].
COPS2C49 F257COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)5.3510.240.0002799900.0018529
Model's repressors:
SymbolAssignmentTitlemin expressionmax expressionmean weightmin weightmax weightNCBI human gene summary
HLXC24 F120H2.0-like homeobox5.1510.64-0.092372-0.092372-0.092372
BATF3C26 F147basic leucine zipper transcription factor, ATF-like 35.829.31-0.069593-0.069593-0.069593
IRF5C25 F135interferon regulatory factor 56.0311.71-0.018732-0.018732-0.018732Summary: This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq].
RELBC32 F174avian reticuloendotheliosis viral (v-rel) oncogene related B6.3111.95-0.016013-0.0262980
ETV3C48 F249ets variant gene 36.7312.57-0.0023952-0.0414550
ZFP219C Fzinc finger protein 2196.419.16-0.0021275-0.00543960