Fine module 32 - Ribosomal proteins


Module's content:

Genes:

SYMBOLTITLEMINMAXNCBI human gene summary
ATP5EATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit7.1410.27NCBI mm gene  
ATP5LATP synthase, H+ transporting, mitochondrial F0 complex, subunit g6.5210.77NCBI mm gene  
GM11810predicted gene 118104.156.84NCBI mm gene  
GM14072predicted gene 140725.909.18NCBI mm gene  
GM6134predicted pseudogene 61345.669.79NCBI mm gene  
GM6394predicted gene 63946.359.97NCBI mm gene  
GM7079ribosomal protein S29 pseudogene7.1412.25NCBI mm gene  
GM7730predicted gene 77307.3510.85NCBI mm gene  
GM8290predicted gene 82906.309.33NCBI mm gene  
INO80INO80 homolog (S. cerevisiae)8.4712.40NCBI mm gene  Summary: The protein encoded by this gene represents the catalytic ATPase subunit of the INO80 chromatin remodeling complex. This complex binds DNA and is recruited by YY1 to activate certain genes.
PFDN5prefoldin 56.8010.18NCBI mm gene  
PIN4protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)6.819.84NCBI mm gene  Summary: This gene encodes a member of the parvulin subfamily of the peptidyl-prolyl cis/trans isomerase protein family. The encoded protein catalyzes the isomerization of peptidylprolyl bonds, and may play a role in the cell cycle, chromatin remodeling, and/or ribosome biogenesis. The encoded protein may play an additional role in the mitochondria. [provided by RefSeq].
PPM1Fprotein phosphatase 1F (PP2C domain containing)6.6210.51NCBI mm gene  
PSMA3proteasome (prosome, macropain) subunit, alpha type 37.1610.14NCBI mm gene  
RPL22L1ribosomal protein L22 like 14.6310.41NCBI mm gene  
RPL35Aribosomal protein L35A8.4712.41NCBI mm gene  Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L35AE family of ribosomal proteins. It is located in the cytoplasm. The rat protein has been shown to bind to both initiator and elongator tRNAs, and thus, it is located at the P site, or P and A sites, of the ribosome. Although this gene was originally mapped to chromosome 18, it has been established that it is located at 3q29-qter. Transcript variants utilizing alternative transcription initiation sites and alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq].
RPL37ribosomal protein L377.9312.27NCBI mm gene  
RPS12ribosomal protein S129.1313.14NCBI mm gene  
RPS21ribosomal protein S217.0011.98NCBI mm gene  
RPS27Aribosomal protein S27A8.5812.74NCBI mm gene  Summary: Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.[provided by RefSeq].
RPS28ribosomal protein S287.7711.28NCBI mm gene  
RPS29ribosomal protein S298.0112.59NCBI mm gene  
SEC61BSec61 beta subunit7.4810.83NCBI mm gene  
SEC61GSEC61, gamma subunit7.3010.75NCBI mm gene  
UQCRHubiquinol-cytochrome c reductase hinge protein8.0811.31NCBI mm gene