| Category | Set
title | Brief
description | Enrichment
p-value | #set
genes
in
module |
|---|
| C1 | 5qF | Genes in cytogenetic band 5qF | 1.0447e-007 | 5 |
| c2 | MOSERLE_IFNA_RESPONSE | Top 50 genes up-regulated in ovarian cancer progenitor cells (also known as side population, SP, cells) in response to interferon alpha (IFNA). | 3.9747e-011 | 5 |
| c2 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP | Genes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928, 3205] off a retroviral vector at 3 days after transduction. | 1.0862e-009 | 6 |
| c2 | MAHADEVAN_RESPONSE_TO_MP470_UP | Top genes up-regulated in the GIST (gastrointestinal stromal tumor) cell line resistant to imatinib [PubChem=5291] after treatment with MP470, a protein kinase inhibitor. | 1.2469e-009 | 4 |
| c2 | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP | Genes up-regulated in CT60/4 cells (breast cancer reverted to normal by transfer of chromosome 8p region) vs parental MDA-MB-231 cells (deleted chromosome 8p). | 1.9545e-009 | 5 |
| c2 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | Genes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928, 3205] off a retroviral vector at 10 days after transduction. | 2.1693e-009 | 6 |
| c2 | BROWNE_INTERFERON_RESPONSIVE_GENES | Genes up-regulated in primary fibroblast culture after treatment with interferon alpha for 6 h. | 2.643e-009 | 5 |
| c2 | ZHANG_INTERFERON_RESPONSE | Interferon-inducible genes up-regulated in A549 cells (lung cancer) infected with a respiratory syncytial virus (RSV) that had its NS1 [Gene ID=1494468] gene knocked down by RNAi. | 3.8025e-009 | 4 |
| c2 | BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS | Genes significantly up-regulated in the blood mononuclear cells from patients with systemic lupus erythematosus compared to those from healthy persons. | 6.0133e-009 | 4 |
| c2 | DAUER_STAT3_TARGETS_DN | Top 50 genes down-regulated in A549 cells (lung cancer) expressing STAT3 [Gene ID=6774] off an adenovirus vector. | 1.8488e-008 | 4 |
| c2 | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN | Genes down-regulated in monocyte-derived dendritic cells (MDDC) after stimulation with galecin-1 (lectin, LGALS1) [Gene ID=3956] compared to that with bacterial lipopolysaccharide (LPS). | 1.8677e-008 | 7 |
| c2 | ZHOU_INFLAMMATORY_RESPONSE_LPS_UP | Genes up-regulated in macrophages by P.gingivalis LPS (lipopolysaccharide). | 3.4099e-008 | 6 |
| c2 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | Genes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928, 3205] off a retroviral vector at 8 days after transduction. | 4.6867e-008 | 5 |
| c2 | FARMER_BREAST_CANCER_CLUSTER_1 | Cluster 1: interferon, T and B lymphocyte genes clustered together across breast cancer samples. | 5.039e-008 | 4 |
| c2 | SANA_TNF_SIGNALING_UP | Genes up-regulated in five primary endothelial cell types (lung, aortic, iliac, dermal, and colon) by TNF [Gene ID=7124]. | 5.9076e-007 | 4 |
| c2 | NUYTTEN_NIPP1_TARGETS_UP | Genes up-regulated in PC3 cells (prostate cancer) after knockdown of NIPP1 [Gene ID=5511] by RNAi. | 1.4969e-006 | 6 |
| c2 | ZHU_CMV_8_HR_UP | Up-regulated at 8 h following infection of primary human foreskin fibroblasts with CMV | 2.1678e-006 | 3 |
| c2 | LIANG_SILENCED_BY_METHYLATION_2 | Genes up-regulated in T24 cells (bladder carcinoma) after treatment with decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]. | 4.1038e-006 | 3 |
| c2 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | Genes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928, 3205] off a retroviral vector at 16 days after transduction. | 6.5422e-006 | 4 |
| c2 | ZHU_CMV_ALL_UP | Up-regulated at any timepoint following infection of primary human foreskin fibroblasts with CMV | 1.4818e-005 | 3 |
| c2 | DER_IFN_ALPHA_RESPONSE_UP | Genes up-regulated in HT1080 cells (fibrosarcoma) by treatment with interferon alpha for 6 h. | 1.5948e-005 | 3 |
| c2 | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP | Genes up-regulated in HEK293 cells (embryonic kidney) at 6 h, 12 h or 24 h after infection with reovirus strain T3A (known as a strong inducer of apoptosis). | 2.0884e-005 | 4 |
| c2 | SANA_RESPONSE_TO_IFNG_UP | Genes up-regulated in five primary endothelial cell types (lung, aortic, iliac, dermal, and colon) by IFNG [Gene ID=3458]. | 2.5476e-005 | 3 |
| c2 | BROWNE_HCMV_INFECTION_8HR_UP | Genes up-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 8 h time point that were not up-regulated at the previous time point, 6 h. | 4.6975e-005 | 3 |
| c2 | DER_IFN_BETA_RESPONSE_UP | Genes up-regulated in HT1080 (fibrosarcoma) cells by treatment with interferon beta for 6 h. | 5.9763e-005 | 3 |
| c2 | UROSEVIC_RESPONSE_TO_IMIQUIMOD | Interferon cluster genes up-regulated in skin tumors treated with imiquimod [PubChem=57469]. | 7.7566e-005 | 2 |
| c2 | MISSIAGLIA_REGULATED_BY_METHYLATION_UP | Genes up-regulated in PaCa44 and CFPAC1 cells (pancreatic cancer) after treatment with decitabine [PubChem=451668], a DNA hypomethylating agent similar to azacitidine [PubChem=9444]. | 7.7889e-005 | 3 |
| c2 | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 | Genes up-regulated in the pancreatic cancer cell lines (AsPC1, Hs766T, MiaPaCa2, Panc1) but not in the non-neoplastic cells (HPDE) by decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]. | 9.2007e-005 | 4 |
| c2 | BOWIE_RESPONSE_TO_TAMOXIFEN | Genes up-regulated by tamoxifen [PubChem=5376] in HMEC-E6 cells (mammary epithelial cells damaged by expression of HPV-16 E6 [Gene ID=1489078]). | 0.00010985 | 2 |