Fine module 269 - -



MsigDB enrichement:
  • C1 - Mouse genomic bands
  • C2 - curated gene sets
  • C3 - motif gene sets
  • C5 - GO gene sets
    CategorySet titleBrief descriptionEnrichment p-value#set genes in module
    C119qC1Genes in cytogenetic band 19qC13.6551e-0064
    c2TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UPGenes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928, 3205] off a retroviral vector at 10 days after transduction.2.1818e-0119
    c2MOSERLE_IFNA_RESPONSETop 50 genes up-regulated in ovarian cancer progenitor cells (also known as side population, SP, cells) in response to interferon alpha (IFNA).3.7139e-0116
    c2TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UPGenes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928, 3205] off a retroviral vector at 3 days after transduction.3.6429e-0108
    c2ZHANG_INTERFERON_RESPONSEInterferon-inducible genes up-regulated in A549 cells (lung cancer) infected with a respiratory syncytial virus (RSV) that had its NS1 [Gene ID=1494468] gene knocked down by RNAi.1.0544e-0095
    c2SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UPGenes up-regulated in CT60/4 cells (breast cancer reverted to normal by transfer of chromosome 8p region) vs parental MDA-MB-231 cells (deleted chromosome 8p).4.1802e-0096
    c2TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UPGenes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928, 3205] off a retroviral vector at 8 days after transduction.4.9572e-0097
    c2DAUER_STAT3_TARGETS_DNTop 50 genes down-regulated in A549 cells (lung cancer) expressing STAT3 [Gene ID=6774] off an adenovirus vector.7.9736e-0095
    c2TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UPGenes up-regulated in CD34+ [Gene ID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [Gene ID=4928, 3205] off a retroviral vector at 16 days after transduction.1.5155e-0087
    c2BROWNE_INTERFERON_RESPONSIVE_GENESGenes up-regulated in primary fibroblast culture after treatment with interferon alpha for 6 h.3.3055e-0075
    c2GOZGIT_ESR1_TARGETS_DNGenes down-regulated in TMX2-28 cells (breast cancer) which do not express ESR1 [Gene ID=2099]) compared to the parental MCF7 cells which do.1.296e-0069
    c2ZHAN_MULTIPLE_MYELOMA_LB_DNTop 50 down-regulated genes in cluster LB of multiple myeloma samples belonging to the low bone disease group.1.579e-0064
    c2FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DNGenes down-regulated in monocyte-derived dendritic cells (MDDC) after stimulation with galecin-1 (lectin, LGALS1) [Gene ID=3956] compared to that with bacterial lipopolysaccharide (LPS).1.9748e-0068
    c2FARMER_BREAST_CANCER_CLUSTER_1Cluster 1: interferon, T and B lymphocyte genes clustered together across breast cancer samples.2.0457e-0064
    c2XU_AKT1_TARGETS_6HRGenes up-regulated in DU-145 cells (prostate cancer) expressing a dominant negative form of AKT1 [Gene ID=207] upon sham-treatment for 6 hr (as a control for the HGF [Gene ID=3082] experiments).4.5502e-0063
    c2TSAI_DNAJB4_TARGETS_UPGenes up-regulated in CL1-5 cells (lung cancer) overexpressing DNAJB4 [Gene ID=11080] off a plasmid vector.4.5502e-0063
    c2BOWIE_RESPONSE_TO_TAMOXIFENGenes up-regulated by tamoxifen [PubChem=5376] in HMEC-E6 cells (mammary epithelial cells damaged by expression of HPV-16 E6 [Gene ID=1489078]).5.9041e-0063
    c2ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UPHepatic graft versus host disease (GVHD), day 7: up-regulated in allogeneic vs syngeneic bone marrow transplant.1.3819e-0055
    c2MARKEY_RB1_ACUTE_LOF_UPGenes up-regulated in adult fibroblasts with inactivated RB1 [Gene ID=5925] by Cre-lox: acute loss of function (LOF) of RB1.1.9445e-0056
    c2WALLACE_PROSTATE_CANCER_RACE_UPGenes up-regulated in prostate cancer samples from African-American patients compared to those from the European-American patients.2.7522e-0056
    c2KRASNOSELSKAYA_ILF3_TARGETS_UPUp-regulated in GHOST(3)CXCR4 cells (osteosarcoma) upon ectopic expression of ILF3 [Gene ID=3609].3.5877e-0053
    c2BROWNE_HCMV_INFECTION_4HR_UPGenes up-regulated in primary fibroblast cell culture point after infection with HCMV (AD169 strain) at 4 h time point that were not up-regulated at the previous time point, 2 h.9.8791e-0053
    c2ROETH_TERT_TARGETS_UPGenes up-regulated in T lymphocytes overexpressing TERT [Gene ID=7015] off a retrovirus vector.0.000118812