Fine module 268 - -


Module's content:

Genes:

SYMBOLTITLEMINMAXNCBI human gene summary
2310035C23RIKRIKEN cDNA 2310035C23 gene6.919.40NCBI mm gene  
4930432O21RIKRIKEN cDNA 4930432O21 gene5.058.71NCBI mm gene  
4931406H21RIKRIKEN cDNA 4931406H21 gene5.608.08NCBI mm gene  
6720487G11RIKzinc finger protein 7385.188.26NCBI mm gene  
A230046K03RIKRIKEN cDNA A230046K03 gene6.8610.34NCBI mm gene  
AFTPHaftiphilin7.3911.41NCBI mm gene  
APCadenomatosis polyposis coli6.209.87NCBI mm gene  Summary: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq].
ARID4AAT rich interactive domain 4A (RBP1-like)6.049.92NCBI mm gene  
ATAD2BATPase family, AAA domain containing 2B6.799.89NCBI mm gene  
B430203M17RIKphosphatase and tensin homolog4.799.43NCBI mm gene  
CEP350centrosomal protein 3506.8710.69NCBI mm gene  
CLK1CDC-like kinase 18.4212.01NCBI mm gene  
GM10397predicted gene 103978.1011.26NCBI mm gene  
JMJD1Cjumonji domain containing 1C6.7911.55NCBI mm gene  
NR3C1nuclear receptor subfamily 3, group C, member 17.0710.20NCBI mm gene  Summary: The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. [provided by RefSeq].
ROCK2Rho-associated coiled-coil containing protein kinase 25.989.92NCBI mm gene  
SETDB2SET domain, bifurcated 24.389.65NCBI mm gene  
SLKSTE20-like kinase (yeast)7.2710.69NCBI mm gene  
TAOK1TAO kinase 16.8910.34NCBI mm gene  
VPS13Bvacuolar protein sorting 13B (yeast)7.1610.11NCBI mm gene  Summary: This gene encodes a potential transmembrane protein that may function in vesicle-mediated transport and sorting of proteins within the cell. This protein may play a role in the development and the function of the eye, hematological system, and central nervous system. Mutations in this gene have been associated with Cohen syndrome. Multiple splice variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq].
ZC3H7Azinc finger CCCH type containing 7 A7.2910.42NCBI mm gene  
ZFC3H1zinc finger, C3H1-type containing6.4911.76NCBI mm gene  
ZFP62zinc finger protein 625.989.56NCBI mm gene  
ZUFSPzinc finger with UFM1-specific peptidase domain5.6110.25NCBI mm gene