Fine module 232 - -


Module's content:

Genes:

SYMBOLTITLEMINMAXNCBI human gene summary
1810007M14RIKGC-rich sequence DNA-binding factor 16.9310.29NCBI mm gene  
A530032D15RIKRIKEN cDNA A530032D15Rik gene7.5510.70NCBI mm gene  
ARHGEF12Rho guanine nucleotide exchange factor (GEF) 125.9010.12NCBI mm gene  
BAZ1Abromodomain adjacent to zinc finger domain 1A7.7110.96NCBI mm gene  
BAZ2Bbromodomain adjacent to zinc finger domain, 2B5.919.92NCBI mm gene  
C130026I21RIKRIKEN cDNA C130026I21 gene5.679.38NCBI mm gene  
C530030P08RIKRIKEN cDNA C530030P08 gene8.8012.90NCBI mm gene  
CCNL1cyclin L17.8311.67NCBI mm gene  
CD2APCD2-associated protein5.8311.22NCBI mm gene  Summary: This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq].
CEP170centrosomal protein 1705.999.93NCBI mm gene  
CSPRScomponent of Sp100-rs4.2610.61NCBI mm gene  
DCLRE1CDNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)5.999.97NCBI mm gene  Summary: This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). [provided by RefSeq].
EIF2AK4eukaryotic translation initiation factor 2 alpha kinase 45.918.77NCBI mm gene  
ELL2elongation factor RNA polymerase II 25.299.75NCBI mm gene  
EPB4.1L2erythrocyte protein band 4.1-like 26.8811.05NCBI mm gene  
FEM1Cfem-1 homolog c (C.elegans)7.7811.13NCBI mm gene  
GDAP10ganglioside-induced differentiation-associated-protein 105.0510.62NCBI mm gene  
GM13570predicted gene 135705.718.51NCBI mm gene  
HIVEP1human immunodeficiency virus type I enhancer binding protein 17.1011.51NCBI mm gene  
HSN2hereditary sensory neuropathy, type II6.0711.67NCBI mm gene  
IQGAP1IQ motif containing GTPase activating protein 16.3712.22NCBI mm gene  
KBTBD7kelch repeat and BTB (POZ) domain containing 75.2710.03NCBI mm gene  
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 16.9511.92NCBI mm gene  
MYO9Amyosin IXa5.6212.23NCBI mm gene  
PAPD4PAP associated domain containing 48.5111.03NCBI mm gene  
PRDM9PR domain containing 95.247.48NCBI mm gene  
RFWD2ring finger and WD repeat domain 27.1510.11NCBI mm gene  
RUFY3RUN and FYVE domain containing 35.648.54NCBI mm gene  
SDCCAG8serologically defined colon cancer antigen 86.149.27NCBI mm gene  
SP140Sp140 nuclear body protein6.4110.68NCBI mm gene  
SPAG9sperm associated antigen 96.9510.81NCBI mm gene  
TET2tet oncogene family member 26.2610.16NCBI mm gene  
THAP6THAP domain containing 65.609.75NCBI mm gene  
TMEM131transmembrane protein 1317.4911.46NCBI mm gene  
TRPS1trichorhinophalangeal syndrome I (human)5.3710.92NCBI mm gene  Summary: This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq].