| Category | Set
title | Brief
description | Enrichment
p-value | #set
genes
in
module |
|---|
| c2 | ALCALAY_AML_BY_NPM1_LOCALIZATION_UP | Genes changed in acute myeloid leukemia (AML) with respect to cellular localization of NPM1 [Gene ID=4869]: cytoplasmic vs. nucleolar. | 2.9785e-008 | 8 |
| c2 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN | Genes down-regulated in normal hematopoietic progenitors by RUNX1-RUNX1T1 [Gene ID=861, 862] fusion. | 2.5104e-006 | 8 |
| c2 | NIKOLSKY_BREAST_CANCER_7P15_AMPLICON | Genes within amplicon 7p15 identified in a copy number alterations study of 191 breast tumor samples. | 3.2633e-005 | 2 |
| c2 | TENEDINI_MEGAKARYOCYTE_MARKERS | Genes essential to the development of megakaryocytes, as expressed in normal cells and essential thrombocythemic cells (ET). | 5.0109e-005 | 4 |
| c2 | ROSS_AML_OF_FAB_M7_TYPE | Top 100 probe sets for pediatric acute myeloid leukemia (AML) subtype FAB M7 (also known as acute megakaryoblastic leukemia, AMKL). | 0.00011165 | 4 |
| c2 | ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN | Genes whose DNA is hyper-methylated in hepatocellular carcinoma (HCC) compared to normal liver. | 0.00011444 | 8 |
| c2 | HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP | Genes up-regulated in hematopoietic progenitor cells (HPC) of T lymphocyte and NK (natural killer) lineage. | 0.00045221 | 4 |
| c2 | MULLIGHAN_NPM1_SIGNATURE_3_UP | The 'NPM1 signature 3': genes up-regulated in pediatric AML (acute myeloid leukemia) with mutated NPM1 [Gene ID=4869] compared to the AML cases with intact NPM1 and MLL [[Gene ID=4297]. | 0.00046631 | 6 |
| c2 | MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_UP | The 'NPM1-mutated signature 2': genes up-regulated in pediatric AML (acute myeloid leukemia) samples with mutated NPM1 [Gene ID=4869] compared to the AML cases with the intact gene and without recurring cytogenetic anomalities or M7 phenotype. | 0.00067588 | 4 |
| c3 | V$GATA1_03 | Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif ANGNDGATAANNGN which matches annotation for GATA1: GATA binding protein 1 (globin transcription factor 1) | 0.00016509 | 5 |
| c3 | V$GATA1_04 | Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif NNCWGATARNNNN which matches annotation for GATA1: GATA binding protein 1 (globin transcription factor 1) | 0.00016509 | 5 |