The Immunological Genome Project (ImmGen) is a collaborative group of immunology and computational biology labs who join forces and expertise to perform a broad and deep dissection of the genome’s activity and its regulation in the immune system of the mouse.
The project defines gene expression signatures and modules, regulatory elements in the genome, their connectivity, and the factors that control them. This as shaped by differentiation, genetic variation and immunologic challenges. These data support the computational reconstruction of the genetic regulatory network underlying immunocyte differentiation and activation.
ImmGen is primarily intended as a public resource. The data and metadata are publicly accessible through ImmGen’s dedicated interfaces.