| Symbol | Assignment | Title | min
expression | max
expression | mean
weight | min
weight | max
weight | NCBI
human
gene
summary |
|---|
| GATA4 | C F | GATA binding protein 4 | 5.69 | 9.07 | 0.067759 | 0 | 0.095885 | Summary: This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects. [provided by RefSeq]. |
| SOX9 | C F | SRY-box containing gene 9 | 5.77 | 10.09 | 0.061974 | 0.061974 | 0.061974 | Summary: The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. [provided by RefSeq]. |
| PAWR | C35 F190 | PRKC, apoptosis, WT1, regulator | 6.16 | 10.66 | 0.053585 | 0.05281 | 0.14002 | |
| NFATC4 | C35 F187 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 4.98 | 8.90 | 0.040381 | 0 | 0.055605 | |
| WWTR1 | C35 F190 | WW domain containing transcription regulator 1 | 5.69 | 10.31 | 0.040213 | 0 | 0.26297 | |
| SOX21 | C F | SRY-box containing gene 21 | 5.69 | 7.81 | 0.035443 | 0.035443 | 0.035443 | |
| TCF15 | C F | transcription factor 15 | 5.62 | 8.78 | 0.020188 | 0 | 0.051037 | |
| FOXE3 | C F | forkhead box E3 | 6.58 | 8.50 | 0.0097946 | 0 | 0.032409 | Summary: This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia. [provided by RefSeq]. |
| KLF15 | C F | Kruppel-like factor 15 | 5.84 | 8.36 | 0.007192 | 0 | 0.023797 | |
| BCL6B | C35 F187 | B-cell CLL/lymphoma 6, member B | 5.12 | 10.25 | 0.0066193 | 0 | 0.131 | |
| KLF1 | C F | Kruppel-like factor 1 (erythroid) | 5.10 | 9.80 | 0.0051151 | 0 | 0.0058126 | Summary: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq]. |
| MEIS2 | C36 F196 | Meis homeobox 2 | 3.91 | 9.98 | 0.0039893 | 0 | 0.1496 | |
| SOX7 | C35 F187 | SRY-box containing gene 7 | 4.95 | 9.34 | 0.0029605 | 0 | 0.11102 | |
| SOX14 | C F | SRY-box containing gene 14 | 5.95 | 7.74 | 0.0017736 | 0 | 0.02217 | |
| INSM1 | C27 F157 | insulinoma-associated 1 | 6.09 | 11.11 | 0.00028903 | 0 | 0.065032 | |
Model's
repressors:
| Symbol | Assignment | Title | min
expression | max
expression | mean
weight | min
weight | max
weight | NCBI
human
gene
summary |
|---|
| CBX3 | C8 F50 | chromobox homolog 3 (Drosophila HP1 gamma) | 5.56 | 11.33 | -0.053809 | -0.053809 | -0.053809 | |
| LZTR1 | C F | leucine-zipper-like transcriptional regulator, 1 | 6.39 | 8.97 | -0.02523 | -0.064509 | 0 | |
| SMAD2 | C F | MAD homolog 2 (Drosophila) | 6.75 | 9.54 | -0.021523 | -0.05503 | 0 | |
| TAF2 | C2 F17 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor | 5.97 | 9.82 | -0.0085706 | -0.10149 | 0 | |
| EED | C45 F225 | embryonic ectoderm development | 6.23 | 9.99 | -0.0010838 | -0.0036948 | 0 | |